Sequelae of radiotherapy and radiotherapy

Nasopharyngeal cancer radiation therapy is the most effective treatment, five-year survival rate after radiotherapy was about 34% to 53%. Radiation therapy can cure properly sequelae little early lesions on the availability of good palliative effect of advanced disease, to have distant metastasis can play a relieve (pain) palliative effect, individual single lung or bone metastasis after radiotherapy can be Long-term survival.
Sequelae of radiotherapy and radiotherapy, although the structure adjacent to the nasopharynx have a high tolerance to radiation, but there will still be some complications caused by the radiation, especially those in sufficient quantities or excessive radiation therapy in patients described as : innocent involvement, spread to neighbors. Radiotherapy sequelae including radioactive xerostomia, the nervous system radiation injury, radiation bone necrosis, radiation injury and nasal Yan radioactive mandibular joint dysfunction, and the most common radiation xerostomia.
Xerostomia is the finger of radioactive and neck cancer receiving radiation therapy due to significant reduction of salivary flow to rapid onset and persistence of dry mouth for the performance. The majority of nasopharyngeal carcinoma patients after radiotherapy with different degrees of saliva reduction, resulting in dry mouth. Sequelae of radiotherapy and radiotherapy, resulting in dry mouth patients is mainly due to three pairs of salivary glands (parotid, under the collar gland, sublingual gland) can be included within the radiation portal, in particular, is the largest salivary gland or two almost all included in the nasopharyngeal primary tumor within radiotherapy field, which to varying degrees by exposure, leading to salivary gland atrophy, reduction in the saliva, there xerostomia. Saliva salivary gland damage and the extent of reduction depends on the irradiation time, dose and type.
Sequelae of radiotherapy and radiation, radioactive radiation xerostomia usually appear in late, and was progressively increased, and is irreversible. Private Prosecution in patients with persistent dry mouth, and sometimes have a burning sensation, diminished sense of taste. Lack of saliva can make chewing and swallowing, difficulty speaking, often associated with oral infection. Some drugs can be used to control the phase mouthwash.


  • radiotherapy sequelae