The proliferation and metastasis of colorectal cancer, 1. Direct the spread of cancer in the bowel wall infiltration within the bowel along the perimeter of the development of easy, low infiltration along the intestinal axis, which is colorectal cancer and inflammatory diseases is one important basis for identification. Pulp mold has the ability to stop the invasion of colorectal cancer, so cancer invasion to the intestinal tissue to the site without serosa majority, that is, around the rectum, ascending colon and descending colon behind.
Colorectal cancer proliferation and metastasis 2. hematogenous invasion of metastatic tumor cells than the invasion of small veins of small arteries and easy, so distant metastasis of colorectal cancer to the portal vein to the liver. In addition to liver metastasis of blood, other organs are also rich in blood supply can occur.
The proliferation and metastasis of colorectal cancer 3. Lymph node metastasis of lymph node metastasis of colorectal cancer is the most common way of spread of colorectal cancer resection specimens in 30% of lymph node metastasis has occurred. Lymphatic vessels in the submucosa and subserosa the most abundant form two lymphatic network, and the muscle in the lymphatic vessels connected. Colon cancer lymph node metastasis occurs first in lymph nodes near the bowel, and then draining to this segment of the supply artery lymph nodes, followed by drainage channels and then arrived in their own superior mesenteric artery or the root node. Rectal lymphatic drainage is divided into short, medium and long categories, drainage to the inferior mesenteric artery root peri rectal lymph node.
The proliferation and metastasis of colorectal cancer 4. Serosal seeding of metastatic tumor cells after soaking off, attached to the parietal peritoneum and other organs within the abdominal cavity surface, grow into small nodules. More common in the pelvic peritoneum, sometimes large areas of diffuse peritoneal metastasis planting, and often accompanied by ascites.
Colorectal cancer may also fall off in the intestinal lumen, in a remote area on the growth of colorectal cancer to another, such cultivation can occur in colorectal mucosa, but more likely in the wound, the stoma, so after colorectal cancer more in the anastomotic recurrence.