The concept of tumor cell factor
The concept of tumor cell factor, the immune cells in cancer patients and non-immune cells can synthesize and secrete peptide class of small molecule factor, which regulate various cellular functions, these factors collectively known as cytokines (cytokines).
Cytokines include lymphokines, macrophages and monocytes produce a single nuclear factor. Interleukin-known (interleukin, IL), interferon (interferon, IFN), colony stimulating factor (colony stimulating factor, CSF), tumor necrosis factor (tumor necrosis factor, TNF), transforming growth factor (transforming growth foctor, TGF) and so is the immune cells to produce cytokines, which in the immune system plays an important regulatory role, in exceptional circumstances can lead to pathological reactions.
1. IL IL (interleukin, IL) is the main. Produced by activated lymphocytes, immune cells can play a regulatory role in a group of small proteins. Has been officially named 30 IL. IL is not only a variety of activated immune cells, chemotaxis, induce cytokines, the role of regulating immune responses, they are also involved in other cells such as hematopoietic stem cells, vascular endothelial cells of blood fly fly fibroblast cells, nerve cells and other interactions.
The concept of tumor cell factor, 2. Colony-stimulating factor during in vitro hematopoietic cells, we found that several cytokines can stimulate hematopoietic stem cells in different semi-solid medium colony-forming cells, these factors are named colony-stimulating factor .