Special type of lung cancer – BAC 1.BAC the general characteristics of histological features: a. the original tumor tissue from destruction of alveolar structural integrity. The original structure as the proliferation of cancer support (scaffold); b. alveoli, alveolar ducts and small bronchiectasis, cavity filled with fluid or slurry, or was empty and the like. Cells were single or multiple, tiled like (pavement), scales like (lepidic) spread along the airway growth; c. may have slightly thickened alveolar septa (the fibrous tissue proliferation or inflammatory cell infiltration), the Central District Since alveolar collapse and fibrosis were small focal; d. cancer cells with varying degrees of atypia, differentiated like normal bronchiolar epithelial cells or alveolar epithelial cells type E; e. both single nodular type, multi-junction section type or diffuse, interstitial infiltration of cancer tissue is not, blood vessels and pleura.
Special type of lung cancer – BAC 2.BAC the general characteristics of the histological type: BAC based on whether cancer cells secrete stalks fluid, and is divided into mucus, non-mucinous and mixed; a. Education bronchioloalveolar carcinoma liquid type (BACmucinOl Time: mucinous type of BAC, BAC the most common type, accounting for 50% of HAC. cancer often within the alveolar space filled with liquid and the expansion of pay; with mild nuclear atypia, nuclear small and deeply stained, accompanied by small nucleolus. b. bronchioloalveolar carcinoma type of non-teaching solution: non-mucinous type of HAC, cancer of the lung cavity, visible light red slurry, a slight expansion of the alveolar cavity; many alveolar carcinoma is empty, only see a small number of shedding of hair cells and particulate. cancerous tissues from the Clara cells and (or) E-type cells in the alveolar structure, the growth along the alveolar walls without interstitial infiltration.
HAC non-mucinous type, the majority belong to a single peripheral nodules, generally alveolar compartment section, and nodules around the boundaries blurred. Cancer in the central area often accompanied by slices of alveolar collapse (collapse) was fibrosis, can be mistaken for epilepsy marks cancer. Non-mucinous HAC, acinar-like tissue appeared, papillary and solid tumor nests, often prompted interstitial infiltration of cancer tissue has been required to make careful examination. c. Education of bronchioloalveolar carcinoma and non-liquid mixed or undetermined type mucinous cell type: This type is very rare by the mucus, mucus cells, and uncertain class of non-feeling package consisting of adenocarcinoma, cancer not associated with growth along the alveolar wall interstitial infiltration.
Special type of lung cancer – BAC 3.BAC the general characteristics of the differential diagnosis: BAC diagnosis diagnostic criteria must be strictly controlled, Xu invasive growth of any kind. Multiple nodular BAC mucinous type, to turn against other gastrointestinal, pay attention to clinical history and growth of invasive carcinoma, the two identification difficult.
Multiple nodular non-mucinous-type BAC, it is necessary and thyroid follicular carcinoma and atypical hyperplasia since the identification of Yang; a. lung metastasis of thyroid follicular carcinoma. Primary thyroid cancer is small, difficult to detect, while the occurrence of lung metastasis, metastasis of thyroid follicles within the company, similar to non-mucinous BAC serous alveolar cavity. The most important difference was in the invasive growth of metastatic cancer, destruction of lung tissue, which is different from the BAC growth. Do thyroglobulin immunohistochemistry also help identify the two; b. atypical gonads students. AAH non-invasive lung epithelial cell proliferation may be associated with some atypia, exactly like the BAC II ~ ~ I} Yau pharynx. Note AAH nodule size when identifying 2-3mm, while the HAC is not small when the tumor masses more than 1cm BAC generally more obvious cell atypia; BAC cells varied, columnar, cuboidal, nail-shaped or dome-shaped, more intensive cell .