Mucoepidermoid carcinoma of the lung diagnosis

By | March 27, 2012

Mucoepidermoid carcinoma of the lung should be with the following tumors.
Mucoepidermoid carcinoma of the lung differential diagnosis of mucoepidermoid carcinoma (MEC) of low malignant (low-grade) and high grade (high) identification: the site occurred between the two, age and histological structure similar to, but the prognosis need not be identified. The main distinguishing point is that cell atypia, mitotic activity, tumor necrosis.
The identification of appropriate surgical specimens. The small pieces of materials in bronchoscopy specimens, not so low grade and high grade difference. New solution because of the high malignant epidermoid carcinoma often there are low malignant epidermoid carcinoma straw liquid ingredients.
Mucoepidermoid carcinoma of the lung differential diagnosis of low grade mucoepidermoid carcinoma (L-MEC) and the identification of mucinous cystadenoma: L-MEC may be associated with significant cystic change, should MeA difference. Identification of the two main points: a. parts: L-MEC occurred in the central hilar area, and around the MCA occurred in the lung area; bL-MEC and adenoid cystic structure than see, the important thing is there is focal scales like cells and intermediate cells, while the MCA but not squamous cells and intermediate cells.
Mucoepidermoid carcinoma of the lung differential diagnosis of low grade mucoepidermoid carcinoma (L-MEC) and mucinous cystadenocarcinoma (MCAC) identification: MCAC form cysts vary in size, covered wall mucus cells were columnar in structure similar to. Point is the difference between them: a. parts: L-MEC in the central hilar area in the bronchial lumen was polypoid growth, infiltration of the surrounding lung parenchyma may be, but in general the boundary was clear. The MCAC, located in the peripheral lung, diffuse infiltration of the surrounding lung mucus, ill-defined; bL-MEC squamous cells and intermediate cells can be seen, while the MCAC is no; c. L-MEC covered wall of the columnar epithelial atypia was not obvious, mucus in the lake but not the teaching medium plexiform shaped cells. The MCAC columnar cells lining the large cyst, the nuclear status of people with different shaped bar of mucous cells.
Mucoepidermoid carcinoma of the lung differential diagnosis of high grade mucoepidermoid carcinoma (H-MEC) and poorly differentiated squamous cell carcinoma (pCC) identification: H-MEC tumors mainly composed of intermediate cells, differentiated squamous cell nests and glands of the small components, and p-SCC similar organizational structure. Histological identification required Note: aP-SCC-like hierarchical structure of cancer nest, H-MEC cells is not in the middle of the structure was divided; bH-MEC, the middle cell sections in addition, a number of slices can always find a small focal points better squamous cell nests and the secretion of mucus cells or adenoid structures; c. mucus staining: the description of protein red card, love the first blue and PAS (by amylase pretreatment) and other staining, H-MEC 11 mucus cells were more common; The poorly differentiated carcinoma, the cytoplasm of only a few see the mucus cells.
Mucoepidermoid carcinoma of the lung H-MEC differential diagnosis of adenocarcinoma of the identification and implementation: although not the formation of solid adenocarcinoma adenoid structures, but relatively diffuse mucus cells. The H-MEC cells containing mucus were focal, and non-bleeding new fluid in the middle of juice and white arrangement of cells; may be found to observe a small well differentiated squamous cells.
Mucoepidermoid carcinoma of the lung differential diagnosis of adenoid structure, but the gland carcinoma more aggressive than the H-MEC, the clinical prognosis is poor, diagnosis should note the difference.

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