Complications of radiotherapy in lung cancer

By | October 31, 2011

Clinical summary of complications of radiotherapy in lung cancer are the following:
Lung cancer radiation therapy complications esophageal injury: radiation esophagitis is more common. Common in about 2 weeks after the start of radiation dose 1O-20Gy pain when eating mainly ,30-40Gy esophageal mucositis pain occurs, it may be around the esophagus and esophageal muscle tissue reaction. When chemotherapy and radiation at the same time when the more serious. Less pain for those who do not deal with whichever is the greater mucosal surface anesthesia used, such as oral administration of 1% procaine solution can often relieve pain. Severe pain should be suspended radiotherapy. Fewer late esophageal injury. However, reported esophageal stricture, adhesion, tube formation collapse rooms and desolate.
complications of radiotherapy in lung cancer heart damage: the heart of the radiation damage generated during the incidence increases with increasing radiation dose. It was reported that when the radiation dose greater than 40Gy, the incidence of heart damage is about 5%, while the radiation dose at 60Gy or more, the rate was 50%. Common heart damage have pericarditis, pericardial effusion, myocarditis and fibrosis. Acute radiation is often subclinical cardiac damage, and can be found in ECG changes and myocardial contractility decreased. ECG changes with ST-T changes in the most common, followed after atrial premature beats, premature ventricular contractions, atrial fibrillation and so on. Therefore, abnormal electrocardiogram on the past, the elderly cardiac insufficiency or arteriosclerosis old who want to reduce the exposure of the heart.
complications of lung cancer radiation therapy lung injury: an early manifestation of radiation-induced lung injury in acute radiation pneumonitis usually late showed pulmonary fibrosis. Shanghai Medical University Cancer Hospital Radiology cases 574 cases, the incidence of acute radiation pneumonitis was 16.7%, pulmonary fibrosis was 50%. Clinical manifestations of acute radiation pneumonitis irritating cough, shortness of breath, fever, chest tightness, dyspnea, and purple knot, etc., often accompanied by lung infection. X ray film density increased within the radiation field of the sheet or mesh shadows, and normal tissue boundaries clear. The treatment of acute radiation pneumonitis is mainly rest, the use of adrenal cortex hormones and the expansion of bronchial medication, if necessary, oxygen, if secondary bacterial infection must be the use of antibiotics. Pulmonary fibrosis may be asymptomatic, or only a slight cough. Later manifested as shortness of breath, difficulty breathing, cough, sputum white foam, the larger volume of pulmonary fibrosis can produce right heart failure. No special treatment of pulmonary fibrosis, general symptomatic treatment. The most effective therapy is to avoid lung damage. Ono of its causes and the lungs, high dose, rapid radiation related. Designed to be more reasonable as far as possible radiation treatment planning.
Complications of radiotherapy in lung cancer myelitis: myelitis generally occurs in radioactive after 2 years after radiotherapy, mainly for post-injury, showing a cross sectional paraplegia. As long as the radiation dose to the spinal cord control of 40Gy in 4 weeks, 20 times the safe range, generally does not produce this complication.


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